Assist. prof. Ancuţa Veronica LUPĂESCU
Field: Chemistry, Biochemistry
Education and Training
- 2016-2020 Doctorate: “Al. I. Cuza ” from Iaşi, Doctoral School of Chemistry, Thesis: “ Analogs of the neuroprotective peptide NAP: synthesis, characterization and interaction with metal ions ”.
- 2014-2016 Master: University “Al. I. Cuza ”from Iaşi, Faculty of Chemistry, Specialization: Chemistry and Biochemistry of Heterocycles, Thesis: “Protein inhibitors and anti-amyloid peptides: detection and characterization techniques ”
- 2011-2014 Bachelor’s degree: “Al. I. Cuza ” from Iaşi, Faculty of Chemistry, Specialization: Technological Biochemistry, Thesis: “ Spectroscopic methods used in analytical biochemistry”
Professional experience
- 2021-present Assistant Professor at the Faculty of Medicine and Biological Sciences, “Ștefan cel Mare” University of Suceava.
- 2020-2021 Researcher in technological biochemistry at the Integrated Research, Development and Innovation Center for Advanced Materials, Nanotechnologies and Distributed Manufacturing and Control Systems (MANSiD) within the “Ștefan cel Mare” University of Suceava.
- 2020-2021 Associate Professor at the Department of Health and Human Development, Faculty of Physical Education and Sports, “Stefan cel Mare” University of Suceava.
- 2018-2019 Research Assistant within the project PN-III-P4-ID-PCE-2016-0376, Financing contract no. 56 / 12.07.2017, ”Conformational changes of peptides in the presence of metal ions and antiamyloid compounds, dependent on time and pH, involved in neurodegenerative diseases, acronym MeticonpH.
Publications in journals with an impact factor
- Lupaescu, A.-V .; Mocanu, C.S .; Drochioiu, G .; Shepherd, C.-I. Zinc Binding to NAP-Type Neuroprotective Peptides: Nuclear Magnetic Resonance Studies and Molecular Modeling. Pharmaceuticals (Q1), 14, 1011, 2021. https://doi.org/10.3390/ph14101011
- Lupaescu, A.V., Humelnicu, I., Petre, B. A., Ciobanu, C.I., Drochioiu, G., Direct evidence for binding of aluminum to NAP anti-amyloid peptide and its analogs, European Journal of Mass Spectrometry, no. 26 (2), pp. 106–116, 2020.
- Lupaescu, AV, Jureschi, M., Ciobanu, CI, Ion, L., Zbancioc, G., Petre, BA, Drochioiu G., FTIR and MS evidence for heavy metal binding to anti-amyloidal NAP-like peptides, International Journal of Peptide Research and Therapeutics, no. 25 (1), pp. 303-309, 2019.
- Jureschi, M. *, Lupaescu, AV *, Ion, L., Petre, BA, Drochioiu G., Stoichiometry of heavy metal binding to peptides involved in Alzheimer’s disease: mass spectrometric evidence, Advancements of Mass Spectrometry in Biomedical Research, 1140, 401-415, 2019. (* – equal contributions)
- Lupaescu, A.V., Sandu, I., Petre, B.A., Ion, L., Ciobanu, C.I., Drochioiu G., NAP neuroprotective peptide and its analogs: Copper and iron binding and reduction, Revista de Chimie, no. 70 (5), pp. 1784-1790, 2019.
- Lupaescu, A.V., Ciobanu, C.I., Humelnicu, I., Petre, B.A., Murariu, M., Drochioiu G., Design and synthesis of new anti-amyloid NAP-based / like peptides, Revue Roumaine de Chimie, no. 64 (6), pp. 535-546, 2019.
- Ion, L., Lupaescu, A.V., Neamtu, A., Drochioiu, G., Petre, B.A., Binding Affinities Studies of Nitrated Model Peptides to Monoclonal Anti-3-nitrotyrosine Antibody, Revista de Chimie, no. 71 (1), pp. 259-265, 2020.