1991- graduation from the “Gr.T.Popa” University of Medicine and Pharmacy,General Medicine
Iasi, Romania
1995- specialist physician in clinical laboratory
1998- PhD in Medicine, Microbiology
2000- attending physician in clinical laboratory
1994 January – March ,scholarship at Ambroise Paré hospital; under the supervision of prof
Marie Héléne Nicolas Chanoine
1996 May October scholarship from BSAC (British Society of Antimicrobial Chemotherapy)-
prof David M. Livermore
1999 August- October- Invited Professor in the programme Conferencia de Alta Nivel Y
Catedras Especiales, Cuernavaca, Morelos, Mexic; Prof. Jesus Silva Sanchez
2004-2005 December- January; 2005-2006- December- February- visiting physician at St Jude
Children’s Research Hospital, Memphis, Tennessee; prof Randall Hayden

HABILITATION: Order of the Ministry of education Nr. 3267/22.01.2024

Teaching experience

1991-2004- “Gr.T.Popa” University of Medicine and Pharmacy iasi, Romania, Microbiology Department; junior instructor- lecturer

2012-2020- associate lecturer at the Stefan cel Mare Suceava University

2020-2022- lecturer at the Faculty of Medicine and Biological Sciences, Stefan cel Mare Suceava University

July 2022- present- associate professor Faculty of Medicine and Biological Sciences, Stefan cel Mare Suceava University

Medical experience

1991-2004- Sfanta Maria Children’s Hospital Iasi, Romania; Sfantul Spiridon University Hospital, Dermatology Clinic Laboratory, Iasi, Romania

2004-2010- Romanian Railway Outpatient Clinic, Suceava ,Romania

2010-present- Hipocrat Clinical laboratory, Suecava, Romania

2018- present-  attending physician, head of laboratory, Tuberculosis and Molecular Biology Laboratory, Suceava Emergency County Hospital

• Microbiology- Technical Dentistry and Medical assistance
• Hygiene- Dietetics and Balneophysio kinetotherapy
• Interpretation of laboratory tests

• Study of the mechanisms of resistance of Enterobacteriaceae to beta-lactam antibiotics; characterization of beta lactamases of circulating strains in Romania and in different areas and medical units in Europe
• Dynamics of resistance of Mycobacterium tuberculosis strains in Eastern Romania, detection and characterization of multidrug-resistant strains
• Definition and role of the molecular biology laboratory in the Covid pandemic; 21st century microbiology; microbiological computing

• Prospective study on the development of a molecular diagnostic laboratory COVID-19 within the clinic of the company CORAMED S.R.L. Suceava; nr.13.793 / 30.07.2020, RON 1904
• Prospective study on the realization of a molecular diagnostic laboratory COVID-19 within the medical analysis laboratory of the company S.C.HipocratS.R.L.Suceava; No. 13730 / 30.07.2020, RON 1904
• Genetic characterization of multiresistant Enterobacteriaceae clinical isolates to antibiotics. National Institute of Public Health, Cuernavaca, Morelos, Mexico

• 2021 Hygiene Practical works. Coordinating editor Roxana Filip, co authors: Liliana Anchidin Norocel, Roxana Gheorghita. Performantica Publishing House, Iasi, http://exlibris.usv.ro:8991F; Editura cotata CNCSIS 1142/3006.2003
•  2021 Hygiene- Course Notes. Roxana Filip, Liliana Anchidin Norocel. Performantica Publishing house, Iasi http://exlibris.usv.ro:8991/F; CNCSIS 1142/30.06.2003
• 2021- Phenotypic and genotypic characterization of beta lactamases produced by Enterobacteriaceae strains circulating in Europe.Performantica Publishing House, ISBN 978-606-685-726-0
• 1999: Treatise on Clinical Microbiology: Chapter: Detection and Identification of Microorganisms by Molecular Biology Methods; nucleic acid probes and gene amplification; pp. 536-556; Medical Publishing
• 2003: Medical Microbiology – Guide to the study and practice of medicine; Gr Popa Publishing House, Iasi
• 1998: Handbook of Medical Microbiology with the author
• 1996: Medical Microbiology co-author

• Clinical management and complications of acute appendicitis in 3 children with SARS-CoV-2 infection

  Case report
  Florin Filip, MD, PhD, Monica Terteliu-Baitan, MD, Ramona Avramia, MD, Roxana Filip, MD, PhD* 
  Maria Elena Cocuz, MD, PhD ;Medicine (2024) 103:43

• “Microbiome and cancer:from mechanistic implications in disease progression and tertamnet to development of novel antitumoral strategies”
  Marian Constantin, Mariana Carmen Chifiriuc, Grigore Mihaescu, Nicolae Corcionivoschi, Liliana Burlibasa, Coralia Bleotu, Sorin Tudorache, Magda Mihaela Mitache, Roxana Filip, Simona Gloria Munteanu, Gratiela Gradisteanu Pircalabioru.
  Front. Immunol., 23 April 2024
  Sec. Microbial Immunology
  Volume 15 – 2024 | https://doi.org/10.3389/fimmu.2024.1373504

• Impact of the COVID-19 pandemic on the realworld diagnostic infrastructure for tuberculosis—An ESGMYC collaborative study” Laura Paulowski, Roxana Filip, Mateja Jankovic Makek, Lorenzo Guglielmetti, Delia Goletti, Jakko van Ingen, Katharina Kranzer, Florian P. Maurer on behalf of ESGMYC PLos ONE 19 (4) e0291404.http://doi.org/10.1371/journal.pone.0291404
• The knowns and unknowns of long COVID-19. :from mechanisms to therapeutical approaches. Roxana Gheorghita, Iuliana Soldanescu, Andrei Lobiuc, Olga Adriana caliman Studrza,Roxana Filip , Adela Constantinescu-Bercu, Mihai Dimian, Serghei Mangul and Mihai Covasa. Front Immunol. 15:1344086. doi:10.3389/fimmu.2024.1344086.
  Publicat in Frontiers in Immunology. Impact factor:7.2
• Role of interferons in the antiviral battle: from virus-host crosstalk to prophylactic and therapeutic potential in SARS CoV-2 infection. Grigore Mihaescu, Mariana Carmen Chifiriuc, Roxana Filip, Coralia Bleotu, Lia Maria Ditu, Marian Constantin, Roxana Elena Cristian, Raluca Grigore, Serban Vifor Bertesteanu, Gloria Bertesteanu and Corneliu Ovidiu Vrancianu. Frontiers in Immunology, 15 January 2024. Front.Immunol.14.1273604. doi:10.3389/fimmu.2023.1273604
• COVID-19 positive cases in a pediatric surgery department from Romania Case series from 2 years of pandemics Florin Filip, Ramona Avramia, Monica Terteliu Baitan   Medicine 2023;102:48(e36235). 
• Innovative Materials with Possible Applications in the Wound Dressings Field: Alginate-Based Films with Moringa oleifera Extract. Roxana Gheorghita, Roxana Filip, Ancuta Veronica Lupaescu, Monica Iavorschi, Liliana  Anchidin-Norocel, Gheorghe Gutt.  Gels 2023, 9, 560. https://doi.org/10.3390/gels9070560
• The Role of the Prognostic Inflammatory and Nutritional Index (PINI) in the Evolution of Patients with Chronic Kidney Disease and Other Pathologies, Monica Cordos , Cristiana-Elena Vlad , Simona-Mihaela Hogas , Roxana Filip  , Gabriela Geletu , Maria Bogdan  , Codruta Badescu  , Ancuta Goriuc  and Liliana Georgeta Foia 4, Healthcare 2023, 11, 1375. https://doi.org/10.3390/ healthcare11101375
• ” Quo Vadis Diagnosis”: Application of Informatics in Early Detection of Pneumothorax V. Dhilip Kumar  , P. Rajesh  , Oana Geman  , Maria Daniela Craciun  , Muhammad Arif  and Roxana Filip  ; Diagnostics 2023, 13, 1305. https://doi.org/10.3390/ diagnostics13071305 
• Acute  Appendicitis in COVID-19-Positive Children: A Report of 4 Cases from an Endemic Area in Northeastern Romania Florin Filip 1, 2, Monica Terteliu Baitan 1,2, Ramona Avramia 1,2 and Roxana Filip 1,2,*https://doi.org/10.3390/ijerhp20010706
• Antiviral immunity in SARS CoV 2 infection:from protective to deleterious responses. Grigore Mihaeascu, mariana Carmen Chifiriuc, Corneliu Ovidiu Vrancianu, Marian Constantin, Roxana Filip, Mihaela Roxana Popescu, Liliana Burlibasa, Anca Cecilia Nicoara, Alexandra Bolocan, Ciprian Iliescu, Gratiela Gradisteanu Pircalabioru. Microorganisms, 2021, 9,2578.
• Elbow septic arthritis caused by Klebsiella pneumoniae in a newborn-case report and literature review. Roxana Filip, Dana Georgeta Laura Murariu, Ramona Avramia, Florin Filip. Revista Romana de Medicina de Laborator, vol 30, nr 3 iulie 2022
• Spontaneous pneumomediastinum in a 16 year old patient with SARS CoV 2 infection: A North East Romanian case. Florin Filip, Monica Terteliu Baitan, Olga Adriana Caliman Sturdza, Roxana Gheorghita Puscaselu and Roxana Filip. Children, 2022, 9, 1641. https://doi.org/10.3390/children9111641
• Chifiriuc MC, Filip R, Constantin M, Pircalabioru GG, Bleotu C, Burlibasa L, Ionica E, Corcionivoschi N and
  Mihaescu G (2022) Common themes in antimicrobial and anticancer drug resistance. Front. Microbiol. 13:960693. doi: 10.3389/fmicb.2022.960693
• Filip, R.; Gheorghita Puscaselu, R.; Anchidin-Norocel, L.; Dimian, M.; Savage, W.K. Global Challenges to Public Health Care Systems during the COVID-19 Pandemic: A Review of Pandemic Measures and Problems. J. Pers. Med. 2022, 12, 1295. https://doi.org/10.3390/jpm12081295
• Mihaescu G, Constantin, M, Andronic C, Bolocan A, Filip R. Anti-cancer alternative therapies: from inorganic nanoparticles to tumor–killing bacteria. Rom. Biotehnol. Lett. 2022; 27(2):3416-3421.
• Vasilescu I. M., Chifiriuc M. C., Pircalabioru G. G., Filip R., Bolocan A., Lazăr V., Diţu L. M., Bleotu C. Gut Dysbiosis and Clostridioides difficile Infection in Neonates and Adults. Front Microbiol. 2022; 12:651081. doi: 10.3389/fmicb.2021.651081
• Dynamics of the communication process at the beginning of the COVID -19 pandemic in Suceava, the first quarantined city in Romania. Dana Humoreanu, Roxana Filip.Meridian Critic nr 1, vol 36/2021
• Applications of biopolymers for drugs and probiotics delivery. Roxana Gheorghita, Liliana Anchidin Norocel, Roxana Filip, Mihai Dimian, Mihai Covasa. Polymers, 2021,13,2729; https://doi.org/10.3390/polym13162729 lucrare premiata UEFSCI.
• Mihaescu G., Chifiriuc M. C., Vrancianu C. O., Constantin M., Filip R., Popescu M. R., Burlibasa L., Nicoara A. C., Bolocan A., Iliescu C., Gradisteanu Pircalabioru G. Antiviral Immunity in SARS-CoV-2 Infection: From Protective to Deleterious Responses. Microorganisms. 2021; 9(12):2578. https://doi.org/10.3390/microorganisms9122578.
• Changes in dietary patterns and clinical health outcomes in different countries during the SARS Cov 2 pandemic. Roxana Filip, Liliana Anchidin Norocel, Roxana Gheorghita,Wesley K.Savage, Mihai Dimian. Nutrients, 2021,13:3612.https://doi.org/10.3390/nu131036.12
• Marqué S, Poirel L, Héritier C, Brisse S, Dolores Blasco, M, Filip, R. et. al. Regional occurrence of plasmid-mediated carbapenem-hydrolyzing oxacillinase OXA-58 in Acinetobacter spp. in Europe. J Clin Microbiol. 2005;43(9):4885-4888.
• Molecular characterization of beta lactam resistance of Salmonella isolates from pediatric patients in Romania; Roxana Filip, Lilia Chihu Amparan, et al. J of Chemotherapy,vol 16 (4): 337-42 August 2004
• Expanded spectrum cephalosporin resistant Salmonella strains in Romania. Vivi Miriagou, Roxana Filip, Gabriela Coman, et al. Journal of Clinical Microbiology, November 2002, vol 40 nr 11, pp 4334-6
• Bases of variation in resistance to beta-lactams in Klebsiella oxytoca isolates hyperproducing K1 beta-lactamase. Roxana Gheorghiu, Meifang Youan, et al. Journal of Antimicrobial Chemotherapy, 1997, 40: 533-41.
• Reduced susceptibility to co-amoxiclav in Escherichia coli, Salmonella typhimurium and Klebsiella pneumoniae isolated in Romania between 1975 and 1993. Florence Espinasse, Roxana Gheorghiu, et al. Journal of Antimicrobial Chemotherapy, 1997, 39: 103-6.
• Prognosis of Ewing sarcoma by quantitative histopathological methods.Roxana Filip, Florin Filip,Laurian Lucian Francu. Paripex Indian Journal of research, vol 7, 9, sept 2018
• Evaluation of angiogenesis in Ewing sarcoma.Florin Filip, Roxana Filip, Laurian Lucian Francu. Paripex Indian Journal of Research,vol 7,10,oct 2018
• Proliferative activity evaluation of osteosarcomas in children. Roxana Filip,laurian Lucian Francu, Florin Filip. Paripex, Indian Journal of research, vol 7, 1, ianuarie 2018
• Antimicrobial susceptibility of Mycoplasma and Ureaplasma strains from genital tract.Roxana Filip, Irina Larisa Iancu, Laurian Lucian francu. Paripex, Indian Journal of Research, vol 7,1, January 2018
• Ultrasonography applications in algo disfunctional syndrome of the temporomandibular joint. M.D.Craciun,C.S.Silisteanu,F.Filip, Roxana FILIP.6th IEEE Conference on E-Health and bioengineering EHB 2017
• The use of CT scan examination in pediatric limb fractures-our experience with two cases. F.Filip, M.Creteanu,M.D.Craciun, Roxana FILIP. 6th IEEE Conference on E-Health and bioengineering EHB 2017
• A two year retrospective study on antibiotic regimens used in children with acute perforated appendicitis. Roxana Filip, D.Stanescu, D.Oprea, F. Filip. 6th IEEE Conference on E-Health and bioengineering EHB 2017

• Honorary Citizen of Suceava – decision of 16.12.2021 
• Abstract reviewer at the congress of the European Society of Microbiology and Infectious Diseases, July 2021; mail ESCMID March 3- March 17, 2021; 
• Abstract reviewer at ECCMID 2022; April 23-26, 2022, Lisbon (proof mail and certified abstract rev) 
• Chair at the Sanofi Pasteur Symposium, Lisbon April2022 
• Grant proposal reviewer for the European Society of Microbiology and Infectious Diseases, ESCMID; 2021 mail esxperiencecmid 
• Trainer within PNBTP Laboratory diagnosis of tuberculosis – course taught as a trainer in the period 1-5 02.2021, within the project POCU / 91/4/8/107488 
• Co chair at the oral session within ECCMID 2021; Tuberculosis treatment: the shorter the better?
• Anastasie Crimca Distinction, June 2022
• Honor Citizen of Suceava county, November 2022

• VII Congreso Panamericana de Historia de la Medicina, XI meteing of the International Association for the History of Medicine, I Congreso Panameno de Historia de la Medicina “Dr. Sebastian Lopez Ruiz”; 2 oral presentations and one sesison as chair
• How Can Pancreatic Stone Protein Improve Sepsis Diagnosis and Management? https://www.youtube.com/watch?v=t_hbKiUkbQo
• Invited speaker at Houston meeting on bacterial resistance against beta lactam antibiotics, November 2022
• National Congress of teh Romanian Society of Microbiology and Epidemiology, 3-5 November 2022, 2 papers as presenting author and co chair oral session
• Days of the Romanian Railway Hospital iasi, Romania, October 2022, 2 papers presented
• Carol Davila University of Medicine and Pharmacy Bucharest Days, November 2022
• Congres sof teh Fcaulty fo Medicien and biological sciences Suceava, Romania, November 2022, 2 papers presented, chair oral sesison
• INTERNATIONAL GÖBEKLİTEPE SCIENTIFIC RESEARCH CONGRESS ” Istanbul, 7-8 octombrie 2022 Quinolone Resistance In Enterobacterales urinary Isolates In An Outpatient Clinic From North Eastern Romania ” ; Biopolymeric Materials With Citrus Essential Oils: Development, Testing And Benefits In Use”
• World sepsis Congress, Belgrade, 12-14 September 2022
• International Society of the History of Medicine Congress,15-16 September 2022 2 presented papers, oral session co chair
• Invited speaker at conference Contagio Agora Infectious Diseases in the context of migration, 3-4 June 2022
• ESCMID appointed co- chair at the Sanofi Pasteur Integrated Symposia “ What matters in the fight against COVID 19: how to keep levels of protection in a multivariant environment? 32 th ECCMID, Lisboa
• Romanian Medical Labroatory Asosciation Conference, May 2022, Brasov Romania oral presentation
• Invited speaker at Antibiotherapy Conference, 8-9 April 2022, Houston
• Iasi Pneumological Days speaker
• Romanian Railway Iasi Hospital Days, 2021, November oral presentation
• 2019- RoVaccin Conference, Bucharest Romania
• 2018- Suceava Medical Days co chair oral session
• 2017 Conference of the Romanian Medical Labroatory Association oral presentation
• 2017- Intenational Conference on Bio Engineering, Sinaia, Romania
• 2016- Conference of the Romanian Medical Labroatory Association oral presentation
• 2016- Conference as invited speaker in Instituto Nacional de Sluad Publica, Cuernavaca Morelos, Mexico
• ECCMID: 2015 Copenhague; 2014 Barcelona, 2013 Berlin,2012 London, 2011 Milan- co chair oral session
• 2009- invited speaker at AMOHP Agrupacion Mexicana de Oncohematologia Pediatrica , Guadalajara Mexic
• ECCMID 2008 Barcelona, 2007 Munich, 2006 Nice, 2005 Copenhague, 2004 Prague, 2003 Glasgow co chair in oral sesisons
• 2007 Director of teh ESCMID Suceava summer school