Conf. univ. habil. dr. Roxana FILIP
Igiena
EDUCAȚIE ȘI FORMARE
1991- absolventa U.M.F.”Gr.T.Popa” Iasi, Facultatea de Medicina
1995- medic specialist laborator clinic, microbiologie, hematologie, parazitologie, biochimie
1998- doctor in medicina, specializarea Microbiologie
2000- medic primar laborator clinic
1994- ianuarie-martie- Paris- bursa de studiu spital Ambroise Paré prof Marie Héléne Nicolas
Chanoine
1996- mai-octombrie- Londra- Royal Hospital Medical College- bursa BSAC (British Society of
Antimicrobial Chemotherapy)- prof David M. Livermore
1999- august- octombrie- Profesor invitat la Cuernavaca Morelos, Conferencia de Alta Nivel y
Catedras Especiales
Decembrie 2004- ianuarie 2005; decembrie 2005- februarie 2006- visiting physician la St Jude
Children,s Research Hospital, Memphis, Tennessee; prof Randall HaydenABILITAT “Se acordà atestatul de abilitare, In domeniul de studii universitare de doctorat Medicinä, doamnei FILIP ROXANA, titular la Universitatea “Stefan cel Mare” din Suceava. Ordinul Ministrului Educatiei, Nr. 3267/22.01.2024
EXPERIENȚA PROFESIONALĂ
Experienta didactica:
1991-2004: cadru didactic U.M.F. “Gr. T.Popa “ Iasi , disciplina de Microbiologie; preparator,
asistent, sef de lucrari
2012-2020- sef lucrari associat Universitatea Stefan cel Mare Suceava, FEFS, DSDU
2020- 2022- sef lucrari titular, FMSB, USV
Oct 2022- present- Conferentiar Universitar, FMSB, USVExperienta Medicala
1991- 2004:Spitalul de copii Sf. Maria Iasi; Spitalul Universitar Sf. Spiridon Iasi, laboratro
Clinica Dermato Venerologie
2004-2010: Spitalul Universitar Cai Ferate Iasi, Ambulatoriu CFR Suceava
2010-prezent: Laborator Hipocrat Suceava
2018- present: Spitalu Judetean de Urgenta “Sf. Ioan cel Nou” Suceava, Laborator BK Biologie
MolecularaDISCIPLINE PREDATE
- Microbiologie- profil AMG si TD
- Igiena- profil ND, BFKT
- Interpretarea analizelor de laborator- profil AMG
DOMENII DE CERCETARE
- Studiul mecanismelor de rezistenta a Enterobacteriaceae-lor la antibioticele beta lactamice; caracterizarea beta lactamazelor tulpinilor circulante in Romania si in diferite zone si unitati medicale din Europa
- Dinamica rezistentei tulpinilor de Mycobacterium tuberculosis in zona Estului Romaniei , depistarea si caracterizarea tulpinilor multirezistente
- Definirea si rolul laboratorului de biologie moleculara in pandemia Covid; microbiologia secolului XXI ; informatica microbiologica
PROIECTE DE CERCETARE COORDONATE:
- Studiu prospectiv privind realizarea unui laborator de diagnostic molecular COVID-19 in cadrul clinicii societatii comerciale CORAMED S.R.L. Suceava; nr.13.793/30.07.2020, RON 1904
- Studiu prospectiv privind realizarea unui laborator de diagnostic molecular COVID-19 in cadrul laboratorului de analize medicale al societatii comerciale S.C.Hipocrat S.R.L.Suceava; nr 13730/30.07.2020,RON 1904
- Genetic characterization of multiresistant Enterobacteriaceae clinical isolates to antibiotics. Instituto Nacional de Salub Publica, Cuernavaca, Morelos , Mexico
PUBLICAȚII (SELECȚIE) Capitole de carte
- Igiena- Lucrări practice Editor coordinator; Roxana Filip; coautori: Liliana Anchidin Norocel, Roxana Gheorghiţă; Editura Performantica Iaşi 2021; înregistrată în catalogul electronic al bibliotecii USV: http://exlibris.usv.ro:8991F
- Igiena Note de curs. Roxana Filip,Liliana Anchidin Norocel. Editura Performantica Iaşi, 2021,ISBN 978-606-685-786-4; înregistrată în catalogul electronic al bibliotecii USV http://exlibris.usv.ro:8991/F
- Carcterizarea fenotipică şi genotipică a beta lactamazelor produse de Enterobacteriaceae circulante în Europa. Roxana Filip. Editura Performantica Iaşi. ISBN 978-606-685-726-0; Editură cotată CNCSIS, 1142/30.06.2003.
- 1999: Tratat de microbiologie clinica: capitolul: Detectarea si identificarea microorganismelor prin metode ale biologiei moleculare; sonde de acizi nucleici si amplificarea genica; pag 536-556; Editura Medicala
- 2003: Microbiologie medicala – Ghid pentru studiul si practica medicinei;
Editura „Gr T Popa” Iasi
- 1998: Manual of Medical Microbiology co autor
- 1996: Medical Microbiology co autor
Publicatii in reviste cu factor de impact
- Clinical management and complications of acute appendicitis in 3 children with SARS-CoV-2 infection
Case report
Florin Filip, MD, PhD, Monica Terteliu-Baitan, MD, Ramona Avramia, MD, Roxana Filip, MD, PhD*
Maria Elena Cocuz, MD, PhD ;Medicine (2024) 103:43 - “Microbiome and cancer:from mechanistic implications in disease progression and tertamnet to development of novel antitumoral strategies”
Marian Constantin, Mariana Carmen Chifiriuc, Grigore Mihaescu, Nicolae Corcionivoschi, Liliana Burlibasa, Coralia Bleotu, Sorin Tudorache, Magda Mihaela Mitache, Roxana Filip, Simona Gloria Munteanu, Gratiela Gradisteanu Pircalabioru.
Front. Immunol., 23 April 2024
Sec. Microbial Immunology
Volume 15 – 2024 | https://doi.org/10.3389/fimmu.2024.1373504
- “Impact of the COVID-19 pandemic on the realworld diagnostic infrastructure for tuberculosis—An ESGMYC collaborative study” Laura Paulowski, Roxana Filip, Mateja Jankovic Makek, Lorenzo Guglielmetti, Delia Goletti, Jakko van Ingen, Katharina Kranzer, Florian P. Maurer on behalf of ESGMYC PLos ONE 19 (4) e0291404.http://doi.org/10.1371/journal.pone.0291404
- The knowns and unknowns of long COVID-19. :from mechanisms to therapeutical approaches. Roxana Gheorghita, Iuliana Soldanescu, Andrei Lobiuc, Olga Adriana caliman Studrza,Roxana Filip , Adela Constantinescu-Bercu, Mihai Dimian, Serghei Mangul and Mihai Covasa. Front Immunol. 15:1344086. doi:10.3389/fimmu.2024.1344086.
Publicat in Frontiers in Immunology. Impact factor:7.2
- Role of interferons in the antiviral battle: from virus-host crosstalk to prophylactic and therapeutic potential in SARS CoV-2 infection. Grigore Mihaescu, Mariana Carmen Chifiriuc, Roxana Filip, Coralia Bleotu, Lia Maria Ditu, Marian Constantin, Roxana Elena Cristian, Raluca Grigore, Serban Vifor Bertesteanu, Gloria Bertesteanu and Corneliu Ovidiu Vrancianu. Frontiers in Immunology, 15 January 2024. Front.Immunol.14.1273604. doi:10.3389/fimmu.2023.1273604
- COVID-19 positive cases in a pediatric surgery department from Romania Case series from 2 years of pandemics Florin Filip, Ramona Avramia, Monica Terteliu Baitan Medicine 2023;102:48(e36235).
- Innovative Materials with Possible Applications in the Wound Dressings Field: Alginate-Based Films with Moringa oleifera Extract. Roxana Gheorghita, Roxana Filip, Ancuta Veronica Lupaescu, Monica Iavorschi, Liliana Anchidin-Norocel, Gheorghe Gutt. Gels 2023, 9, 560. https://doi.org/10.3390/gels9070560
- The Role of the Prognostic Inflammatory and Nutritional Index (PINI) in the Evolution of Patients with Chronic Kidney Disease and Other Pathologies, Monica Cordos , Cristiana-Elena Vlad , Simona-Mihaela Hogas , Roxana Filip , Gabriela Geletu , Maria Bogdan , Codruta Badescu , Ancuta Goriuc and Liliana Georgeta Foia 4, Healthcare 2023, 11, 1375. https://doi.org/10.3390/ healthcare11101375
- ” Quo Vadis Diagnosis”: Application of Informatics in Early Detection of Pneumothorax V. Dhilip Kumar , P. Rajesh , Oana Geman , Maria Daniela Craciun , Muhammad Arif and Roxana Filip ; Diagnostics 2023, 13, 1305. https://doi.org/10.3390/ diagnostics13071305
- Acute Appendicitis in COVID-19-Positive Children: A Report of 4 Cases from an Endemic Area in Northeastern Romania Florin Filip 1, 2, Monica Terteliu Baitan 1,2, Ramona Avramia 1,2 and Roxana Filip 1,2,*https://doi.org/10.3390/ijerhp20010706
- Antiviral immunity in SARS CoV 2 infection:from protective to deleterious responses. Grigore Mihaeascu, mariana Carmen Chifiriuc, Corneliu Ovidiu Vrancianu, Marian Constantin, Roxana Filip, Mihaela Roxana Popescu, Liliana Burlibasa, Anca Cecilia Nicoara, Alexandra Bolocan, Ciprian Iliescu, Gratiela Gradisteanu Pircalabioru. Microorganisms, 2021, 9,2578.
- Elbow septic arthritis caused by Klebsiella pneumoniae in a newborn-case report and literature review. Roxana Filip, Dana Georgeta Laura Murariu, Ramona Avramia, Florin Filip. Revista Romana de Medicina de Laborator, vol 30, nr 3 iulie 2022
- Spontaneous pneumomediastinum in a 16 year old patient with SARS CoV 2 infection: A North East Romanian case. Florin Filip, Monica Terteliu Baitan, Olga Adriana Caliman Sturdza, Roxana Gheorghita Puscaselu and Roxana Filip. Children, 2022, 9, 1641. https://doi.org/10.3390/children9111641
- Chifiriuc MC, Filip R, Constantin M, Pircalabioru GG, Bleotu C, Burlibasa L, Ionica E, Corcionivoschi N and
Mihaescu G (2022) Common themes in antimicrobial and anticancer drug resistance. Front. Microbiol. 13:960693. doi: 10.3389/fmicb.2022.960693 - Filip, R.; Gheorghita Puscaselu, R.; Anchidin-Norocel, L.; Dimian, M.; Savage, W.K. Global Challenges to Public Health Care Systems during the COVID-19 Pandemic: A Review of Pandemic Measures and Problems. J. Pers. Med. 2022, 12, 1295. https://doi.org/10.3390/jpm12081295
- Mihaescu G, Constantin, M, Andronic C, Bolocan A, Filip R. Anti-cancer alternative therapies: from inorganic nanoparticles to tumor–killing bacteria. Rom. Biotehnol. Lett. 2022; 27(2):3416-3421.
- Vasilescu I. M., Chifiriuc M. C., Pircalabioru G. G., Filip R., Bolocan A., Lazăr V., Diţu L. M., Bleotu C. Gut Dysbiosis and Clostridioides difficile Infection in Neonates and Adults. Front Microbiol. 2022; 12:651081. doi: 10.3389/fmicb.2021.651081
- Sindromul burn out În timpul pandemiei COVID19. Roxana Filip, Florin Filip. Bucovina Medicala, an VI,nr 1-4 (21-24)/2020
- Diagnosticul de laborator in infectia cu SARS CoV 2- actualitati si provocari. Roxana Filip. Bucovina Medicala, an VI,nr 1-4 (21-24)/2020
- Dynamics of the communication process at the beginning of the COVID -19 pandemic in Suceava, the first quarantined city in Romania. Dana Humoreanu, Roxana Filip.Meridian Critic nr 1, vol 36/2021
- Applications of biopolymers for drugs and probiotics delivery. Roxana Gheorghita, Liliana Anchidin Norocel, Roxana Filip, Mihai Dimian, Mihai Covasa. Polymers, 2021,13,2729; https://doi.org/10.3390/polym13162729 lucrare premiata UEFSCI.
- Mihaescu G., Chifiriuc M. C., Vrancianu C. O., Constantin M., Filip R., Popescu M. R., Burlibasa L., Nicoara A. C., Bolocan A., Iliescu C., Gradisteanu Pircalabioru G. Antiviral Immunity in SARS-CoV-2 Infection: From Protective to Deleterious Responses. Microorganisms. 2021; 9(12):2578. https://doi.org/10.3390/microorganisms9122578.
- Changes in dietary patterns and clinical health outcomes in different countries during the SARS Cov 2 pandemic. Roxana Filip, Liliana Anchidin Norocel, Roxana Gheorghita,Wesley K.Savage, Mihai Dimian. Nutrients, 2021,13:3612.https://doi.org/10.3390/nu131036.12
- Marqué S, Poirel L, Héritier C, Brisse S, Dolores Blasco, M, Filip, R. et. al. Regional occurrence of plasmid-mediated carbapenem-hydrolyzing oxacillinase OXA-58 in Acinetobacter spp. in Europe. J Clin Microbiol. 2005;43(9):4885-4888.
- Molecular characterization of beta lactam resistance of Salmonella isolates from pediatric patients in Romania; Roxana Filip, Lilia Chihu Amparan, et al. J of Chemotherapy,vol 16 (4): 337-42 August 2004
- Expanded spectrum cephalosporin resistant Salmonella strains in Romania. Vivi Miriagou, Roxana Filip, Gabriela Coman, et al. Journal of Clinical Microbiology, November 2002, vol 40 nr 11, pp 4334-6
- Bases of variation in resistance to beta-lactams in Klebsiella oxytoca isolates hyperproducing K1 beta-lactamase. Roxana Gheorghiu, Meifang Youan, et al. Journal of Antimicrobial Chemotherapy, 1997, 40: 533-41.
- Reduced susceptibility to co-amoxiclav in Escherichia coli, Salmonella typhimurium and Klebsiella pneumoniae isolated in Romania between 1975 and 1993. Florence Espinasse, Roxana Gheorghiu, et al. Journal of Antimicrobial Chemotherapy, 1997, 39: 103-6.
- Prognosis of Ewing sarcoma by quantitative histopathological methods.Roxana Filip, Florin Filip,Laurian Lucian Francu. Paripex Indian Journal of research, vol 7, 9, sept 2018
- Evaluation of angiogenesis in Ewing sarcoma.Florin Filip, Roxana Filip, Laurian Lucian Francu. Paripex Indian Journal of Research,vol 7,10,oct 2018
- Proliferative activity evaluation of osteosarcomas in children. Roxana Filip,laurian Lucian Francu, Florin Filip. Paripex, Indian Journal of research, vol 7, 1, ianuarie 2018
- Antimicrobial susceptibility of Mycoplasma and Ureaplasma strains from genital tract.Roxana Filip, Irina Larisa Iancu, Laurian Lucian francu. Paripex, Indian Journal of Research, vol 7,1, January 2018
- Ultrasonography applications in algo disfunctional syndrome of the temporomandibular joint. M.D.Craciun,C.S.Silisteanu,F.Filip, Roxana FILIP.6th IEEE Conference on E-Health and bioengineering EHB 2017
- The use of CT scan examination in pediatric limb fractures-our experience with two cases. F.Filip, M.Creteanu,M.D.Craciun, Roxana FILIP. 6th IEEE Conference on E-Health and bioengineering EHB 2017
- A two year retrospective study on antibiotic regimens used in children with acute perforated appendicitis. Roxana Filip, D.Stanescu, D.Oprea, F. Filip. 6th IEEE Conference on E-Health and bioengineering EHB 2017
- Clinical management and complications of acute appendicitis in 3 children with SARS-CoV-2 infection
Alte activități
16.12.2021- CETATEAN DE ONOARE AL MUNICIPIULUI SUCEAVA- HOTARAREA NR 304/16.12.2021
2.06.2022- ORDINUL IMTROPOLITUL ANASTASIE CRIMCA PENTRU JERTFA IN FOLOSUL SEMENILOR IN TIMPUL PANDEMIEI SARS COV 2.
28.11.2022 CETATEAN DE ONOARE AL JUDETULUI SUCEAVA -PENTRU LUPTA IN PRIMA LINIE IN TIMPUL PANDEMIEI SARS COV 2Participări congrese
- VII -lea Congres Panamerican de Istoria Medicinei si a XI-a conferinta a Asociatiei Internationale de Istoria Medicinei la Facultatea de Medicina a Universitatii Panamá, Ciudad de Panamá 2 lucrari stiintifice si conducere sesiune orala.
- How Can Pancreatic Stone Protein Improve Sepsis Diagnosis and Management. https://www.youtube.com/watch?v=t_hbKiUkbQo
- Speaker invitat la manifestarea Houston, 4.11.22. mecanisme de rezistenta la antibiotice beta lactamaze.
- Congresul National al Societatiii Romane de Microbiologie si Epidmeiologie, SRME 3-5 noiembrie 2022 presenting
author 2 lucrari si co chair sesiune orala - Zilele Spitalului Universitar CFR Iasi, 2 lucrari prezentate , oct 2022
- Zilele UMF Carol Davila Bucuresti, 10-12 noiembrie 2022
- Congresul FMSB Suecava, noiembrie 2022- 2 lucrari prezentate, chair sesiune orala
- INTERNATIONAL GÖBEKLİTEPE SCIENTIFIC RESEARCH CONGRESS " Istanbul, 7-8 octombrie 2022 Quinolone
Resistance In Enterobacterales urinary Isolates In An Outpatient Clinic From North Eastern Romania " ; Biopolymeric
Materials With Citrus Essential Oils: Development, Testing And Benefits In Use" - World sepsis Congress, Belgrade, 12-14 September 2022
- ISHM 15-8 sept 2022; co chair sesiune orala; 2 lucrari prezentate
- 2022 speaker invitat Conferinta Contagio Agora Bolile Infecto contagioase in conetxtul migratiei accelerate, 3-4 iunie
2022 - Aprilie 2022- ECCMID appointed chair la simpozionul integrat Sanofi Pasteur “What matters in the fight against COVID
19: how to keep high levels of protection in a multivariant environment?, 32 ECCMID, Lisboa - Conferinta AMLR Brasov, mai 2022,lucrare prezentare orala
- 2022 speaker invitat Conferinta de Antibioterapie -Antibioterapia intre uz si abuz, 8-9 aprilie 2022; Houston
- 2021 Zilele Pneumologiei Iesene- speaker
2021 noiembrie Conferinta nationala cu participare internationala Zilele Spitalului CFR Iasi- prezentare orala - 2019 16 martie Conferinta Ro Vaccin Bucuresti
- 2018 Zilele Medicale ale Sucevei co chair sesiune orala
- 2017- conferinta AMLR Timisoara lucrari publicate in volum de rezumate cotat ISI
- Iunie 2017- conferinta Bioinginerie EHB Sinaia
- 2016-Conferinta Asociatiei de Medicina de laborator, Cluj mai 2016 lucrare publicata in volum rezumate cotat ISI
- 2016 septembrie Conferinta la INSP Cuernavaca, Mexic invited speaker
- 2015 ECCMID Copenhaga
- 2014 ECCMID Barcelona
- 2013- ECCMID Berlin
- Zilele Medicale ale Sucevei co-chair sesiune orala: 2013,2015,2021,2022
- 2012- ECCMID Londra 31.03- 3.04
- 2012- Zilele Medicale ale Sucevei, co chair sesiune de comunicari
- 2011- co chair sesiune orala ECCMID Milan, mai 2011
- 2009- Speaker invitat la AMOHP (Agrupacion Mexicana de Oncohematologia Pediatrica) Guadalajera, Mexic
- 2008: coordonator sesiune orala ECCMID Barcelona, aprilie
- 2007: organizator ESCMID summer school- Suceava, Romania-gazda: USV
- 2007- coorodnator sesiune orala la ECCMID Munchen
- 2006- coordonator sesiune orala ECCMID Nice
- 2005- coordonator sesiune orala ECCMID Copenhaga
- 2004- coordonator sesiune orala ECCMID Praga
- 2003- coordonator sesiune orala ECCMID Glasgow
- 2003- Faculty member la summer school ESCMID, Utrecht, Olanda
- 2002- Faculty member la ESCMID summer school, Lausanne
- 1999- Profesor invitat la INSP Cuernavaca Morelos, Mexic- august- octombrie 1999